1. Start with a null model
A statistical test often asks how surprising our observed difference would be under a null hypothesis such as “the methods have equal expected performance.”
A small p-value means the data would be unusual under that null model. It is not the probability that the null hypothesis is true.
2. Significance is not importance
With enough data, a tiny practically irrelevant difference can be statistically detectable. Always report effect size and uncertainty alongside significance.
statistical question: is the difference distinguishable from noise?
practical question: is the difference worth caring about?
3. Use paired evidence when appropriate
If A and B are evaluated on the same examples or same seeds, tests that use pairing can remove much irrelevant variation. The exact test depends on metric, sampling design and assumptions.
4. Multiple comparisons
Try enough architectures, datasets and metrics and some “significant” result may occur by chance. Pre-specified hypotheses, correction methods and transparent reporting reduce this danger.
What to Remember
Statistical significance is one tool for quantifying evidence—not a magic stamp of truth. Effect size, uncertainty, design quality and practical consequences matter too.
Next → How to Avoid Cherry-Picking: how can an entire experimental workflow accidentally manufacture a success story?